Observed herb/drug interactions associated with Dan Shen (Salvia miltiorrhiza). [Source]

Patient Abstract Herb and Use Drug Believed to Interact Other Drugs Being Taken Medical Observation Mechanism Legitimacy
66 year old man with atrial fibrillation, rheumatic mitral stenosis, cerebral embolism, and gastric adenocarcinoma [40] Danshen Salvia miltiorrhiza (Cardiovascular disease) Warfarin Digoxin, propranolol, topical oil containing 15% salicylates ↑ INR; gastric bleeding but additive action due to coumarin content of herb Probably no interaction Possible
62 year old man with mitral valve replacement [41] Danshen Salvia miltiorrhiza (Cardiovascular disease) Warfarin Digoxin, frusemide, captopril ↑ INR but additive action due to coumarin content of herb Probably no interaction Likely
48 year old woman with a history of rheumatic heart disease, mitral stenosis and atrial fibrillation [42] Danshen Salvia miltiorrhiza (Cardiovascular disease) Warfarin Digoxin frusemide, theophylline, mefenamic acid ↑ INR but additive action due to coumarin content of herb Probably no interaction Possible