Bupleurum and Chih-shih Formula (si ni san)


please choose carefully whether capsules or powder and sizes. Thanks.

SKU: SNS Category:


Details of Bupleurum and Chih-shih Formula
Bupleurum unsticks what is stuck.

Bupleurum unsticks what is stuck.

Alternative Names

  • Cold Limbs Powder
  • Cold Extremities Powder
  • Frigid Extremities Powder
  • si ni san
  • szu ni san
  • Counterflow Cold Powder
  • sigyaku san
  • shigyakusan
  • Shigyaku-san
  • 四逆散
  • しぎゃくさん
  • TJ35; TJ-35; TJ 35
  • sì nì sǎn wán
  • 四逆散丸

This is the base formula for liver qi constraint/ stagnation. It forms the root of Xiao Yao Wan and its more popular younger sister: Jia Wei Xiao Yao Wan. The four extremities coldness is known as (a mild case) jue/ reversal where the yang is constrained from getting to the limbs.


  • relaxes tense muscles that cause a sense of dull stuffiness in the upper abdomen.
  • regulates sleeping for those having difficulty falling asleep or staying asleep.
  • As the English name suggests- this formula is also for those who have cold hands and feet. This is caused when a person’s moods cause the “qi” to bind up and the energy can’t circulate. Energy can’t get to the extremities and so they feel cold. Clearing this bound up qi/energy also helps the moods.


Chai Hu 柴胡 hare’s ear root, thorowax root, bupleurum Radix Bupleuri [caution]

Bai Shao 白芍 white peony root, peony Paeoniae Radix alba [supports pregnancy]

  • These two herbs “spread the Liver qi (chai hu) and nourish the Liver (bai shao)” They’re often used together to harmonize the functions of the nervous system. As the name of this formula implies, it is for cold hands and feet. When the nervous system is harmonious (dare I say, less “nervous”), the blood can better circulate to the hands and feet.

Zhi Shi 枳實 unripe bitter orange, chih-shih Aurantii Fructus immaturus [use caution if pregnant]

  • This herb also helps with qi movement, but it is mostly focused on the abdomen for intestinal movements.

Zhi Gan Cao 炙甘草 licorice root Radix Glycyrrhizae prep. [caution]

  • This herb helps soften the harsh properties of the other herbs in this formula to prevent side-effects.

Recommended for these body types:


Slightly Hearty

Slightly Hearty



Recommended for these thermal natures:






Adult Dosage
    Eagle Herbs is now supplying a 2 gram “little spoon”. (Please wash and dry before using.)
    • An “average dose” is 10 grams per day of the granules. This means 5 “little spoons” or 20 capsules each day. Each capsule is 1/2 gram. 
    • A Big Dosage for Short-lived but intense issues: 3 little spoons (12 capsules) twice a day.
    • A Smaller Dosage for Lingering low-grade concerns: 2 little spoons (8 capsules) twice a day. 
    • If you are very sensitive to medicines: start out low (1/2 little spoon or 2 capsules) once per day, and raise the dosage each day.

    We find that people find the right dosage for themselves. We don’t know your body weight, your sensitivity etc… So take what feels good for you and you get the results you are looking for. Many people get great results with taking less. 

    Your order will last approximately this long:

    • 50 grams powder (100 capsules) : 4 to 14 days.
    • 100 grams powder (200 capsules) : 8 to 28 days


Additional information

Weight 120 g
Dimensions 0.2 × 0.2 × 0.2 in
granules or capsules sizes

100 grams granules: $34, 200 grams granules: $60, 100 capsules (50 grams): $35, 200 capsules (100 grams): $58, 5 bottles 200 grams granules: $275, 5 bottles 200 capsules: $260

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